Tag: narrow therapeutic index

Why Some People React Differently to Generic Medications

Generic medications save billions, but for some people, switching to a generic can trigger serious side effects. Why? Inactive ingredients and tiny differences in absorption matter-especially for drugs with narrow therapeutic indices like levothyroxine and warfarin.

How Different Countries Regulate NTI Generics: A Global Comparison

NTI generics require strict regulatory oversight due to their narrow safety margin. This article compares how the U.S., EU, Canada, and Japan regulate these high-risk drugs - and why global alignment is urgently needed.